Artificial intelligence (AI) is changing the art world. But how do you create a work of art with an AI machine? What do terms like "machine learning" and "deep learning" mean? The purpose of the book is to answer these and many other very topical questions, offering the reader an in-depth overview of how today Artificial Intelligence has become a tool in the production of works of art and an ally in research and fruition during the visit of an exhibition. The book is structured in two parts. The first explains how AI is used today in the world of art, up to the latest studies on the detection of our brain reactions in front of an artistic work. The second part is instead an invitation to discover the pioneers in the application of AI thanks to a series of exclusive interviews that include the famous musician and producer Brian Eno, François Pachet (Sony, Spotify), the artists Mario Klingemann, Mike Tyka, Anna Ridler and Mauro Martino; Piero Poccianti (director of the Italian Association for Artificial Intelligence); Julia Betancour (director of Conservation Lab, Collection Solo, Madrid); Andrea Concas (Art Backers and Art Rights) and numerous other exponents of the business, academic and applied research world.